Searchable abstracts of presentations at key conferences in endocrinology

ea0063p17 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Unilateral non-haemorrhagic adrenal infarction (NHAI) as a cause of abdominal pain during pregnancy

Chasseloup Fanny , Bourcigaux Nathalie , Christin-Maitre Sophie

Adrenal infarction is usually associated with bilateral adrenal hemorrhage in the setting of antiphospholipid syndrome or hemodynamic variation. A few cases of unilateral non-hemorrhagic adrenal infarction (NHAI) have been described in the literature. Here, we report a case of unilateral non-haemorrhagic adrenal infarction occurring during pregnancy and a literature review of this clinical entity. A 30-year-old woman presented at 32 weeks of gestation with sudden-onset right a...

ea0063gp245 | Disturbances of Reproduction | ECE2019

MRI detection of aortic anomalies in 204 adult patients with Turner syndrome: a longitudinal study

Donadille Bruno , Tuffet Sophie , Bourcigaux Nathalie , Nedelcu Mariana , Monnier-Cholley Laurence , Rousseau Alexandra , Christin-Maitre Sophie , And Heart Study Group Turner

Mortality is 3 fold higher in patients with Turner syndrome (TS) than in the general population, primarily due to cardiovascular complications. Recent clinical guidelines (Gravholt et al. EJE 2017) underlined the need of a lifelong cardiovascular follow-up. However, prospective studies evaluating the aortic natural history in clinical practice are scarce. We performed a monocentric longitudinal study including 204 adult TS patients, between 2005 and 2018. Inclusion criteria we...

ea0049gp148 | Male Reproduction and Endocrine Disruptors | ECE2017

Impacts of a single ablative dose of radio iodine therapy for differentiated thyroid carcinoma on testicular function: results from the SAPIRA study

Bourcigaux Nathalie , Rubino Carole , Berthaut Isabelle , Donadille Bruno , Toubert Marie Elisabeth , Leenhardt Laurence , Corone Catherine , Petrot-Keller Isabelle , Brailly-Tabard Sylvie , Beaufaron Julie , Simon Tabassome , Siffroi Jean-Pierre , De Vathaire Florent , Sclumberger Martin , Bouchard Philippe , Christin-Maitre Sophie

Background: Radioactive iodine therapy (RAI) is a classical therapeutic approach in patients with differentiated thyroid carcinoma (DCT). Few data are currently available on RAI’s potential impacts on testicular function.Design: A longitudinal prospective multi-center study (PHRC N°P040419) included male patients before a single radioiodine dose of 3.7 GBq of I 131 (V0), at 3 months (V3) and 13 months (V13) post treatment.<p clas...

ea0037gp.30.01 | Endocrine tumours and neoplasia – General | ECE2015

Temozolomide treatment for pituitary aggressive tumours and pituitary carcinomas: initial results and long-term follow-up of a cohort of 32 cases

Lasolle Helene , Castinetti Frederic , Cortet Christine , Cloix Lucie , Batisse-Lignier Marie , Bonnet Fabrice , Bourcigaux Nathalie , Chabre Olivier , Chanson Philippe , Delemer Brigitte , Lebrun-Frenay Christine , Garcia Cyril , Reznik Yves , Schillo Franck , Taillandier Luc , Maiter Dominique , Sadoul Jean-Louis , Caron Philipe , Raverot Gerald

Context: Successful used of temozolomide (TMZ) treatment has been described in 40–50% of aggressive pituitary tumour (PT) or rare pituitary carcinoma. These results are based on 50 case-reports and small series, data on long-term follow-up being rare.Objectives: To describe initial results and long-term follow-up of a large French cohort of patients presenting PT treated with temozolomide.Design: Members of the French Society ...